UNLP de La Plata is an Argentine sports club based in the city of La Plata, Buenos Aires. The club is best known for its professional football team, which currently plays in the Primera División, the top division of the Argentine football league system.

UNLP de La Plata was formed in 1906, just two years after the founding of the city of La Plata. The club's early years were relatively unsuccessful, as they failed to win any major trophies. However, in the 1920s, the club began to find its footing and won its first Primera División title in 1925.

Since then, UNLP de La Plata has been one of the most successful teams in Argentine football, winning a total of 11 Primera División championships. The club has also won a number of other domestic trophies, including the Copa de la Liga Profesional de Fútbol and the Supercopa, as well as international competitions such as the Copa Libertadores and the Copa Sudamericana.

UNLP de La Plata is one of the most popular football teams in Argentine, and its home games at the Estadio Juan Carmelo Zerillo are often sellouts. The club has a strong following both domestically and internationally, and is considered to be one of the top teams in South America.

Some of the club's most famous players include:

* Juan Sebastián Verón
* Javier Zannetti
* Juan Pablo Carrizo
* Sergio Agüero
* Mauro Icardi