| Primera B, Apertura, Promotion, Group A | 2022/05/10 13:15 | Real Santuario v Envigado FC Reserves | W | 1-3 |
| Primera B, Apertura, Promotion, Group A | 2022/04/13 13:00 | Envigado FC Reserves v Independiente Sabaneta | W | 1-0 |
| Primera B, Apertura, Promotion, Group A | 2022/03/21 21:32 | Molino Viejo v Envigado FC Reserves | D | 0-0 |
| Primera B, Apertura, Promotion, Group A | 2022/03/08 13:17 | Envigado FC Reserves v Talento y Vida | D | 0-0 |
| Primera B, Apertura, Promotion, Group A | 2021/12/04 19:20 | Envigado FC Reserves v Molino Viejo | W | 1-0 |
| Primera B, Apertura, Promotion, Group A | 2021/11/16 15:00 | Envigado FC Reserves v CD Los Del Sur | W | 2-1 |
| Primera B, Apertura, Promotion, Group A | 2021/10/24 21:00 | Inder Girardota v Envigado FC Reserves | D | 1-1 |
| Primera B, Apertura, Promotion, Group A | 2021/10/06 16:00 | Independiente Sabaneta v Envigado FC Reserves | W | 0-2 |
| Primera B, Apertura, Promotion, Group A | 2022/04/23 17:18 | Real Santuario v FC Leones Reserves | D | 2-2 |
| Primera B, Apertura, Promotion, Group A | 2022/04/08 15:12 | FC Leones Reserves v Universidad de Antioquia | W | 3-2 |
| Primera B, Apertura, Promotion, Group A | 2022/02/28 16:29 | Molino Viejo v FC Leones Reserves | L | 2-0 |
| Primera B, Apertura, Promotion, Group A | 2021/11/29 16:00 | Independiente Sabaneta v FC Leones Reserves | W | 4-5 |
| Primera B, Apertura, Promotion, Group A | 2021/10/01 17:00 | FC Leones Reserves v Estudiantes de Medellin | W | 2-0 |
| Primera B, Apertura, Promotion, Group A | 2021/09/04 23:00 | FC Leones Reserves v Molino Viejo | W | 2-0 |
| Primera B, Apertura, Promotion, Group A | 2021/07/03 13:00 | FC Leones Reserves v Sellos Colombianos | W | 5-0 |
| Primera B, Apertura, Promotion, Group A | 2021/06/26 12:00 | Independiente Sabaneta v FC Leones Reserves | W | 1-2 |