Stadium: Memorial Stadium Round: 1
| NCAA Division I, FCS, Playoffs | 2023/09/03 00:00 | Colorado State Pueblo Thunderwolves v Midwestern State Mustangs | L | 37-8 |
| NCAA Division I, FCS, Playoffs | 2022/11/12 19:00 | Midwestern State Mustangs v Angelo State | L | 19-37 |
| NCAA Division I, FCS, Playoffs | 2022/11/06 00:00 | Texas AM Kingsville Javelinas v Midwestern State Mustangs | W | 37-41 |
| NCAA Division I, FCS, Playoffs | 2022/10/30 00:00 | Midwestern State Mustangs v Western Oregon Wolves | W | 26-21 |
| NCAA Division I, FCS, Playoffs | 2022/10/22 23:00 | Texas-Permian Basin Falcons v Midwestern State Mustangs | W | 23-24 |
| NCAA Division I, FCS, Playoffs | 2022/10/16 01:00 | Central Washington v Midwestern State Mustangs | L | 17-10 |
| NCAA Division I, FCS, Playoffs | 2022/10/09 00:00 | Midwestern State Mustangs v West Texas AM Buffaloes | L | 26-38 |
| NCAA Division I, FCS, Playoffs | 2022/10/02 00:00 | Western New Mexico v Midwestern State Mustangs | L | 30-27 |
| NCAA Division I, FCS, Playoffs | 2023/08/31 22:00 | Keiser University Seahawks v Mississippi | W | 14-17 |
| NCAA Division I, FCS, Playoffs | 2022/11/12 20:00 | Mississippi v West Florida Argonauts | L | 21-56 |
| NCAA Division I, FCS, Playoffs | 2022/11/05 19:00 | West Alabama Tigers v Mississippi | L | 38-16 |
| NCAA Division I, FCS, Playoffs | 2022/10/29 23:00 | Mississippi v Delta State Statesmen | L | 38-52 |
| NCAA Division I, FCS, Playoffs | 2022/10/22 21:00 | West Florida Argonauts v Mississippi | L | 45-17 |
| NCAA Division I, FCS, Playoffs | 2022/10/15 19:00 | Valdosta State Blazers v Mississippi | W | 40-49 |
| NCAA Division I, FCS, Playoffs | 2022/10/08 19:00 | Mississippi v Shorter Hawks | W | 35-21 |
| NCAA Division I, FCS, Playoffs | 2022/10/01 22:00 | West Georgia Wolves v Mississippi | W | 38-39 |