Stadium: Fisher Stadium Round: 1
Home Manager: John Troxell Away Manager: Mark Fabish
| NCAA Division I, FCS, Playoffs | 2022/11/19 18:00 | Cornell Big Red v Columbia Lions | W | 22-45 |
| NCAA Division I, FCS, Playoffs | 2022/11/12 17:00 | Columbia Lions v Brown Bears | W | 31-24 |
| NCAA Division I, FCS, Playoffs | 2022/11/05 17:00 | Columbia Lions v Harvard Crimson | W | 21-20 |
| NCAA Division I, FCS, Playoffs | 2022/10/28 22:30 | Yale v Columbia Lions | L | 41-16 |
| NCAA Division I, FCS, Playoffs | 2022/10/22 17:30 | Dartmouth Big Green v Columbia Lions | L | 27-24 |
| NCAA Division I, FCS, Playoffs | 2022/10/15 17:00 | Columbia Lions v Pennsylvania | L | 14-34 |
| NCAA Division I, FCS, Playoffs | 2022/10/08 17:00 | 와그너 시호크스 v Columbia Lions | W | 7-28 |
| NCAA Division I, FCS, Playoffs | 2022/10/01 17:00 | Princeton Tigers v Columbia Lions | L | 24-6 |
| NCAA Division I, FCS, Playoffs | 2023/09/09 22:00 | Lafayette v 듀크 | L | 7-42 |
| NCAA Division I, FCS, Playoffs | 2023/09/09 22:00 | Lafayette v Old Dominion | L | 31-38 |
| NCAA Division I, FCS, Playoffs | 2023/09/03 00:30 | Northwestern State v Lafayette | W | 13-38 |
| NCAA Division I, FCS, Playoffs | 2023/09/02 22:00 | Lafayette v Sacred Heart Pion. | W | 19-14 |
| Collegiate Bowl Games | 2022/12/23 20:00 | Houston v Lafayette | L | 23-16 |
| NCAA Division I, FCS, Playoffs | 2022/11/26 22:00 | Lafayette v Texas State | W | 41-13 |
| NCAA Division I, FCS, Playoffs | 2022/11/19 17:30 | 레하이 마운틴 호크스 v Lafayette | W | 11-14 |
| NCAA Division I, FCS, Playoffs | 2022/11/19 17:00 | Lafayette v Florida State | L | 17-49 |