Stadium: Tullio Field Round: 1
| NCAA Division I, FCS, Playoffs | 2022/11/05 18:00 | Seton Hill Griffins v Mercyhurst Lakers | L | 7-0 |
| NCAA Division I, FCS, Playoffs | 2021/10/09 16:00 | Mercyhurst Lakers v Seton Hill Griffins | L | 17-19 |
| NCAA Division I, FCS, Playoffs | 2019/10/19 16:00 | Mercyhurst Lakers v Seton Hill Griffins | L | 20-30 |
| NCAA Division I, FCS, Playoffs | 2018/10/13 16:00 | Seton Hill Griffins v Mercyhurst Lakers | L | 34-33 |
| NCAA Division I, FCS, Playoffs | 2023/10/28 16:00 | California Vulcans v Mercyhurst Lakers | L | 58-19 |
| NCAA Division I, FCS, Playoffs | 2023/10/21 19:00 | Mercyhurst Lakers v Gannon University Golden Knights | L | 28-31 |
| NCAA Division I, FCS, Playoffs | 2023/10/14 16:00 | Clarion University Golden Eagles v Mercyhurst Lakers | W | 35-36 |
| NCAA Division I, FCS, Playoffs | 2023/10/07 18:00 | Mercyhurst Lakers v Slippery Rock | L | 31-75 |
| NCAA Division I, FCS, Playoffs | 2023/09/30 18:00 | Edinboro Fighting Scots v Mercyhurst Lakers | L | 40-24 |
| NCAA Division I, FCS, Playoffs | 2023/09/23 17:00 | Mercyhurst Lakers v Iup Crimson Hawks | L | 13-30 |
| NCAA Division I, FCS, Playoffs | 2023/09/16 16:00 | Kutztown Golden Bears v Mercyhurst Lakers | L | 47-14 |
| NCAA Division I, FCS, Playoffs | 2023/09/09 22:00 | Mercyhurst Lakers v Lock Haven U. BE | W | 41-29 |
| NCAA Division I, FCS, Playoffs | 2023/10/28 16:00 | Seton Hill Griffins v Edinboro Fighting Scots | W | 38-28 |
| NCAA Division I, FCS, Playoffs | 2023/10/21 19:00 | Seton Hill Griffins v Iup Crimson Hawks | W | 35-28 |
| NCAA Division I, FCS, Playoffs | 2023/10/14 19:30 | California Vulcans v Seton Hill Griffins | L | 41-14 |
| NCAA Division I, FCS, Playoffs | 2023/10/07 18:00 | Clarion University Golden Eagles v Seton Hill Griffins | W | 17-24 |
| NCAA Division I, FCS, Playoffs | 2023/09/30 20:00 | Seton Hill Griffins v Gannon University Golden Knights | L | 6-23 |
| NCAA Division I, FCS, Playoffs | 2023/09/23 19:00 | Seton Hill Griffins v Slippery Rock | L | 14-35 |
| NCAA Division I, FCS, Playoffs | 2023/09/16 17:05 | East Stroudsburg Warriors v Seton Hill Griffins | L | 55-21 |
| NCAA Division I, FCS, Playoffs | 2023/09/09 16:00 | Seton Hill Griffins v Shippensburg Raiders | W | 28-23 |