Stadium: Allgood-Bailey Stadium Round: 1
| NCAA Division I, FCS, Playoffs | 2022/11/12 19:00 | Missouri S&T v Southwest Baptist | L | 17-24 |
| NCAA Division I, FCS, Playoffs | 2022/10/29 22:00 | Indianapolis Greyhounds v Missouri S&T | L | 42-16 |
| NCAA Division I, FCS, Playoffs | 2022/10/22 18:00 | Missouri S&T v Mckendree | L | 35-42 |
| NCAA Division I, FCS, Playoffs | 2022/10/15 18:00 | William Jewell v Missouri S&T | W | 14-41 |
| NCAA Division I, FCS, Playoffs | 2022/10/08 19:00 | Truman State v Missouri S&T | L | 36-14 |
| NCAA Division I, FCS, Playoffs | 2022/10/02 00:00 | Missouri S&T v Quincy Hawks | W | 31-24 |
| NCAA Division I, FCS, Playoffs | 2022/09/24 23:00 | Missouri S&T v Hillsdale Chargers | L | 10-17 |
| NCAA Division I, FCS, Playoffs | 2022/09/18 00:00 | Kentucky Wesleyan College Panthers v Missouri S&T | L | 11-6 |
| NCAA Division I, FCS, Playoffs | 2022/11/26 19:30 | Delta State Statesmen v West Florida Argonauts | L | 27-38 |
| NCAA Division I, FCS, Playoffs | 2022/11/19 19:00 | Delta State Statesmen v Fayetteville State Broncos | W | 51-0 |
| NCAA Division I, FCS, Playoffs | 2022/11/12 20:00 | Delta State Statesmen v West Alabama Tigers | W | 17-7 |
| NCAA Division I, FCS, Playoffs | 2022/11/05 19:00 | Delta State Statesmen v West Georgia Wolves | L | 42-52 |
| NCAA Division I, FCS, Playoffs | 2022/10/29 23:00 | Mississippi v Delta State Statesmen | W | 38-52 |
| NCAA Division I, FCS, Playoffs | 2022/10/20 23:00 | Shorter Hawks v Delta State Statesmen | W | 10-45 |
| NCAA Division I, FCS, Playoffs | 2022/10/15 23:00 | Delta State Statesmen v West Alabama Tigers | W | 20-7 |
| NCAA Division I, FCS, Playoffs | 2022/10/08 17:00 | North Greenville University Crusaders v Delta State Statesmen | W | 14-47 |