Stadium: Armfield Athletic Center Round: 1
| NCAA Division I, FCS, Playoffs | 2022/09/03 16:00 | Greensboro Pride v Guilford Quakers | W | 37-48 |
| NCAA Division I, FCS, Playoffs | 2021/09/04 23:00 | Guilford Quakers v Greensboro Pride | W | 21-7 |
| NCAA Division I, FCS, Playoffs | 2022/11/12 18:00 | Guilford Quakers v Bridgewater Eagles | L | 22-64 |
| NCAA Division I, FCS, Playoffs | 2022/11/05 17:00 | Averett Cougars v Guilford Quakers | W | 0-26 |
| NCAA Division I, FCS, Playoffs | 2022/10/29 17:00 | Hampden Sydney Tigers v Guilford Quakers | L | 28-21 |
| NCAA Division I, FCS, Playoffs | 2022/10/22 17:00 | Guilford Quakers v Ferrum Panthers | L | 17-31 |
| NCAA Division I, FCS, Playoffs | 2022/10/15 17:00 | Shenandoah Hornets v Guilford Quakers | L | 38-35 |
| NCAA Division I, FCS, Playoffs | 2022/10/08 18:00 | Guilford Quakers v Washington And Lee Generals | L | 6-31 |
| NCAA Division I, FCS, Playoffs | 2022/10/01 17:00 | Randolph Macon Yellow Jackets v Guilford Quakers | L | 48-19 |
| NCAA Division I, FCS, Playoffs | 2022/09/17 17:00 | Guilford Quakers v Huntingdon Hawks | L | 7-47 |
| NCAA Division I, FCS, Playoffs | 2022/11/12 18:00 | Greensboro Pride v Nc Wesleyan Battling Bishops | L | 14-35 |
| NCAA Division I, FCS, Playoffs | 2022/11/05 22:00 | Methodist Monarchs v Greensboro Pride | L | 48-23 |
| NCAA Division I, FCS, Playoffs | 2022/10/29 18:00 | Huntingdon Hawks v Greensboro Pride | L | 42-0 |
| NCAA Division I, FCS, Playoffs | 2022/10/15 16:00 | Greensboro Pride v Belhaven Blazers | L | 7-59 |
| NCAA Division I, FCS, Playoffs | 2022/10/08 16:00 | Greensboro Pride v Southern Virginia Knights | W | 38-28 |
| NCAA Division I, FCS, Playoffs | 2022/09/30 23:30 | Brevard Tornados v Greensboro Pride | L | 31-13 |
| NCAA Division I, FCS, Playoffs | 2022/09/24 16:00 | Greensboro Pride v Maryville Scots | L | 17-37 |
| NCAA Division I, FCS, Playoffs | 2022/09/17 17:00 | Hampden Sydney Tigers v Greensboro Pride | L | 70-28 |