티그레스 FC U20

The history of the club began in 2002, when Expreso Palmira was purchased by businessmen who renamed the club Expreso Rojo de Cartagena. The team won the Primera C championship in that same year.

In 2003 the club played its first season in Primera B under the Expreso Rojo name, placing first in the aggregate table but being eliminated in the play-offs. Two years later the club moved to Sincelejo, where they only lasted a year, returning to Cartagena in 2006. In the 2007 season the team moved to the city of Fusagasugá, Cundinamarca.

The club's most notable participation in Colombian football occurred in the 2008 Copa Colombia in which the club reached the semi-finals. Expreso Rojo was eliminated by Once Caldas at that stage, with a 1–0 aggregate score.

In 2009 the team moved to Zipaquirá due to economic problems. For the 2011 season Expreso Rojo decided to move back to Fusagasugá, however due to poor results the club moved once again, this time to Soacha. In 2014 the team moved to Girardot, only to return to Zipaquirá the following year due to the poor state of the playing field in Girardot.

For the following season (2016), the club was renamed as Tigres F.C. due to a ruling by the Superintendency of Industry and Commerce of Colombia stating that the Expreso Rojo brand was already trademarked and linked to top-flight club Independiente Santa Fe and therefore could not be used by any other company. In that season, they earned promotion to Categoría Primera A for the 2017 season by winning Group A in the Primera B semi-finals. They became season runners-up after losing the final to América de Cali on aggregate score. However, they were relegated back to Primera B after only one season in the top flight.